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3D Imaging of Pharmaceutical Formulations
Microstructure characterisation of blends
Crystallographic tomography and molecular modelling
Quantifying lactose microstructure through XCT
Parmesh Gajjar, Ioanna Danai Styliari, Victoria Legh-Land, Hrishikesh Bale, Benjamin Tordoff, Philip J Withers, Darragh Murnane
European Journal of Pharmaceutics and Biopharmaceutics 191, 265-275. (2023)
Quantifying lactose microstructure through XCT
Crystallographic tomography and molecular modelling
Quantifying lactose microstructure through XCT
Parmesh Gajjar, Ioanna Danai Styliari, TTH Nguyen, J Carr, X Chen, JA Elliott, RB Hammond, TL Burnett, K Roberts, PJ Withers, Darragh Murnane
European Journal of Pharmaceutics and Biopharmaceutics 151, 32-44. (2020)
Crystallographic tomography and molecular modelling
Crystallographic tomography and molecular modelling
Crystallographic tomography and molecular modelling
Parmesh Gajjar, Thai TH Nguyen, Jun Sun, Ioanna D Styliari, Hrishikesh Bale, Samuel A McDonald, Timothy L Burnett, Benjamin Tordoff, Erik Lauridsen, Robert B Hammond, Darragh Murnane, Philip J Withers, Kevin J Roberts
CrystEngComm 23 (13), 2520-2531. (2021)
Molecular modelling of blends with XCT insight
Particle packing through XCT for powder flow and consolidation
Crystallographic tomography and molecular modelling
Cai Y Ma, Thai TH Nguyen, Parmesh Gajjar, Ioanna D Styliari, Robert B Hammond, Philip J Withers, Darragh Murnane, Kevin J Roberts
Molecular Pharmaceutics 20 (10), 5019-5031. (2023)
Understanding hexamine agglomeration
Particle packing through XCT for powder flow and consolidation
Particle packing through XCT for powder flow and consolidation
Thai TH Nguyen, Parmesh Gajjar, Jun Sun, Robert B Hammond, Darragh Murnane, Benjamin Tordoff, Erik Lauridsen, Philip J Withers, Kevin J Roberts
Journal of Crystal Growth 603, 126986. (2023)
Particle packing through XCT for powder flow and consolidation
Particle packing through XCT for powder flow and consolidation
Particle packing through XCT for powder flow and consolidation
Thomas D Turner, Parmesh Gajjar, IS Fragkopoulos, James Carr, TTH Nguyen, D Hooper, F Clarke, N Dawson, PJ Withers, KJ Roberts
Crystal Growth & Design, 20 (7), 4252-4263. (2020)
Imaging breakage of high-aspect ratio crystals
Imaging breakage of high-aspect ratio crystals
Imaging breakage of high-aspect ratio crystals
FM Mahdi, AP Shier, IS Fragkopoulos, James Carr, Parmesh Gajjar, FL Muller
Pharmaceutical Research 37 (12). (2020)
Peer Reviewed Conference Proceedings
Inhalation Blend Microstructure: Identifying Metrics to Address Q3 Equivalence using Semi-Automated X-Ray Microscopy
Parmesh Gajjar, Ioanna Danai Styliari, Victoria Legh-land, Hrishikesh Bale, Benjamin Tordoff, Philip J Withers, Darragh Murnane.
Respiratory Drug Delivery Europe 2023, 125-134
Link: https://www.rddonline.com/rdd/article.php?id=0&sid=103&ArticleID=3006&return=1
Unlocking secrets of inhalation blends through X-ray Computed Tomography and Microscopy
Hrishikesh Bale, Robert Hammond, Parmesh Gajjar, Ioanna Danai Styliari, Philip Withers, Darragh Murnane
Microscopy and Microanalysis 27 (S1), 292-295
https://doi.org/10.1017/S1431927621001628
From Particles to Powders: Digital Approaches to Understand Structure and Powder Flow of Inhaled Formulations
Parmesh Gajjar, Thai TH Nguyen, Ioanna Danai Styliari, Vivian W Barron, Timothy Burnett, Xizhong Chen, Simon D Connell, James A Elliott, Robert Hammond, FM Mahdi, Kevin Roberts, Philip Withers, Darragh Murnane
Respiratory Drug Delivery Europe 2021
Link: https://www.rddonline.com/rdd/article.php?id=0&sid=103&ArticleID=2780&return=1
Laboratory Diffraction Contrast Tomography (LabDCT): A new technique for measuring crystal habit and formulation structure
Hrishikesh Bale, Jun Sun, Parmesh Gajjar, Erik Lauridsen, Darragh Murnane, Hien Nguyen, Kevin Roberts, Benjamin Tordoff, Philip J Withers
Respiratory Drug Delivery 2020
Link: https://www.rddonline.com/rdd/article.php?id=0&sid=103&ArticleID=2769&return=1
Unlocking the Microstructure of Inhalation Blends using X-Ray Microscopy
Parmesh Gajjar, Hrishikesh Bale, Timothy Burnett, Xizhong Chen, James A Elliot, Herminso Villarraga Gomez, Robert B Hammond, Hien Nguyen, Kevin J Roberts, Ioanna Danai Styliari, Benjamin Tordoff, Philip Withers, Darragh Murnane
Respiratory Drug Delivery 2020, 101-112
Link: https://www.rddonline.com/rdd/article.php?id=0&sid=103&ArticleID=2656&return=1
On Measuring the Specific Surface Area of Inhalation-grade Lactose Powders
Ioanna Danai Styliari, Thai TH Nguyen, Parmesh Gajjar, Benjamin Tordoff, Tim L Burnett, Philip J Withers, Robert B Hammond, Kevin J Roberts, Darragh Murnane
Respiratory Drug Delivery 2020, 551-554
Link: https://www.rddonline.com/rdd/article.php?id=0&sid=103&ArticleID=2728&return=1
X-ray Computed Tomography: A 3D method for characterising inhalation powders
Parmesh Gajjar, Ioanna Danai Styliari, Timothy Burnett, Xizhong Chen, James A. Elliot, William J. Ganley, Robert Hammond, Hien Nguyen, Robert Price, Kevin Roberts, Philip Withers, Darragh Murnane
Drug Delivery to the Lungs 2019
https://doi.org/10.1089/jamp.2020.ab01.abstracts
Multiscale Tomography: Probing the Nano-, Micro-, and Meso-scale Resolution of Inhalation Powder Structure
Parmesh Gajjar, Ioanna Danai Styliari, Tim L. Burnett, Xizhong Chen, James A Elliott, Will Ganley, Robert B Hammond, Thai TH Nguyen, Rob Price, Kevin J Roberts, Philip J Withers, Darragh Murnane
Respiratory Drug Delivery Europe 2019, 155-168
Link: https://www.rddonline.com/rdd/article.php?id=0&sid=103&ArticleID=2582&return=1