Resources - Informix Pharma

Resources

Conference Presentations

Characterisation of powder microstructure inside blisters using 3D X-ray Imaging

Conference: Drug Delivery to the Lungs, [2024], Vol 35, 171-174

Author(s): Parmesh Gajjar, Amin Garbout, Philip J. Withers, Darragh Murnane

Exploring Inhalation Blend Pre-Actuation Microstructure using X-Ray Computed Tomography: Properties, Processing and Performance

Conference: Respiratory Drug Delivery Asia 2024, [2024] 54-64

Author(s): Parmesh Gajjar, Ioanna Danai Styliari, Philip J. Withers, Darragh Murnane

Novel Insight into the Microstructure of Fines-Only Formulations using X-ray Computed Tomography with Machine Learning

Conference: Respiratory Drug Delivery 2024, [2024] 275-278

Author(s): Parmesh Gajjar, Alex Wimbush, Hrishikesh Bale, Nicolas Gueninchault, Benjamin Tordoff, Philip J. Withers, Darragh Murnane

Inhalation Blend Microstructure: Identifying Metrics to Address Q3 Equivalence using Semi-Automated X-Ray Microscopy

Conference: Respiratory Drug Delivery Europe 2023, [2023] 125-134

Author(s): Parmesh Gajjar, Ioanna Danai Styliari, Victoria Legh-land, Hrishikesh Bale, Benjamin Tordoff, Philip J Withers, Darragh Murnane.

Unlocking secrets of inhalation blends through X-ray Computed Tomography and Microscopy

Conference: Microscopy and Microanalysis 27 (S1), [2021], 292-295

Author(s): Hrishikesh Bale, Robert Hammond, Parmesh Gajjar, Ioanna Danai Styliari, Philip Withers, Darragh Murnane

From Particles to Powders: Digital Approaches to Understand Structure and Powder Flow of Inhaled Formulations

Conference: Respiratory Drug Delivery Europe 2021 [2021]

Author(s): Parmesh Gajjar, Thai TH Nguyen, Ioanna Danai Styliari, Vivian W Barron, Timothy Burnett, Xizhong Chen, Simon D Connell, James A Elliott, Robert Hammond, FM Mahdi, Kevin Roberts, Philip Withers, Darragh Murnane

Laboratory Diffraction Contrast Tomography (LabDCT): A new technique for measuring crystal habit and formulation structure

Conference: Respiratory Drug Delivery 2020 [2020]

Author(s): Hrishikesh Bale, Jun Sun, Parmesh Gajjar, Erik Lauridsen, Darragh Murnane, Hien Nguyen, Kevin Roberts, Benjamin Tordoff, Philip J Withers

Unlocking the Microstructure of Inhalation Blends using X-Ray Microscopy

Conference: Respiratory Drug Delivery 2020, [2020] 101-112

Author(s): Parmesh Gajjar, Hrishikesh Bale, Timothy Burnett, Xizhong Chen, James A Elliot, Herminso Villarraga Gomez, Robert B Hammond, Hien Nguyen, Kevin J Roberts, Ioanna Danai Styliari, Benjamin Tordoff, Philip Withers, Darragh Murnane

On Measuring the Specific Surface Area of Inhalation-grade Lactose Powders

Conference: Respiratory Drug Delivery 2020, [2020] 551-554

Author(s): Ioanna Danai Styliari, Thai TH Nguyen, Parmesh Gajjar, Benjamin Tordoff, Tim L Burnett, Philip J Withers, Robert B Hammond, Kevin J Roberts, Darragh Murnane

X-ray Computed Tomography: A 3D method for characterising inhalation powders

Conference: Drug Delivery to the Lungs 2019 [2019]

Author(s): Parmesh Gajjar, Ioanna Danai Styliari, Timothy Burnett, Xizhong Chen, James A. Elliot, William J. Ganley, Robert Hammond, Hien Nguyen, Robert Price, Kevin Roberts, Philip Withers, Darragh Murnane

Journal Articles

Microstructural insight into inhalation powder blends through correlative multi-scale X-ray Computed Tomography

Journal: European Journal of Pharmaceutics and Biopharmaceutics 191, 265-275. (2023)

Author(s): Parmesh Gajjar, Ioanna Danai Styliari, Victoria Legh-Land, Hrishikesh Bale, Benjamin Tordoff, Philip J Withers, Darragh Murnane

Predicting the Strength of Cohesive and Adhesive Interparticle Interactions for Dry Powder Inhalation Blends of Terbutaline Sulfate with α-Lactose Monohydrate

Journal: Molecular Pharmaceutics 20 (10), 5019-5031. (2023)

Author(s): Cai Y Ma, Thai TH Nguyen, Parmesh Gajjar, Ioanna D Styliari, Robert B Hammond, Philip J Withers, Darragh Murnane, Kevin J Roberts

Structure, morphology and surface properties of α-lactose monohydrate in relation to its powder properties

Journal: Journal of Pharmaceutical Sciences 114, 507-519. (2025)

Author(s): Thai T. H. Nguyen, Cai Y. Ma, Ioanna D. Styliari, Parmesh Gajjar, Robert B. Hammond, Philip J. Withers, Darragh Murnane, Kevin J. Roberts,

Understanding the agglomerate crystallisation of hexamine through X-ray microscopy and crystallographic modelling

Journal: Journal of Crystal Growth 603, 126986. (2023)

Author(s): Thai TH Nguyen, Parmesh Gajjar, Jun Sun, Robert B Hammond, Darragh Murnane, Benjamin Tordoff, Erik Lauridsen, Philip J Withers, Kevin J Roberts

Crystallographic tomography and molecular modelling of structured organic polycrystalline powders

Journal: CrystEngComm 23 (13), 2520-2531. (2021)

Author(s): Parmesh Gajjar, Thai TH Nguyen, Jun Sun, Ioanna D Styliari, Hrishikesh Bale, Samuel A McDonald, Timothy L Burnett, Benjamin Tordoff, Erik Lauridsen, Robert B Hammond, Darragh Murnane, Philip J Withers, Kevin J Roberts

On the breakage of high aspect ratio crystals in filter beds under continuous percolation

Journal: Pharmaceutical Research 37 (12). (2020)

Author(s): FM Mahdi, AP Shier, IS Fragkopoulos, James Carr, Parmesh Gajjar, FL Muller

Measuring the Particle Packing of l-Glutamic Acid Crystals through X-ray Computed Tomography for Understanding Powder Flow and Consolidation Behavior

Journal: Crystal Growth & Design, 20 (7), 4252-4263. (2020)

Author(s): Thomas D Turner, Parmesh Gajjar, IS Fragkopoulos, James Carr, TTH Nguyen, D Hooper, F Clarke, N Dawson, PJ Withers, KJ Roberts

3D Characterisation of Dry Powder Inhaler Formulations: Developing X-ray Micro Computed Tomography Approaches

Journal: European Journal of Pharmaceutics and Biopharmaceutics 151, 32-44. (2020)

Author(s): Parmesh Gajjar, Ioanna Danai Styliari, TTH Nguyen, J Carr, X Chen, JA Elliott, RB Hammond, TL Burnett, K Roberts, PJ Withers, Darragh Murnane